depmap
Query the Cancer Dependency Map (DepMap) for cancer cell line gene dependency scores (CRISPR Chronos), drug sensitivity data, and gene effect profiles. Use for identifying cancer-specific vulnerabilities, synthetic lethal interactions, and validating oncology drug targets.
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---
name: depmap
description: Query the Cancer Dependency Map (DepMap) for cancer cell line gene dependency scores (CRISPR Chronos), drug sensitivity data, and gene effect profiles. Use for identifying cancer-specific vulnerabilities, synthetic lethal interactions, and validating oncology drug targets.
license: CC-BY-4.0
metadata:
skill-author: Kuan-lin Huang
---
# DepMap — Cancer Dependency Map
## Overview
The Cancer Dependency Map (DepMap) project, run by the Broad Institute, systematicHow to Use
Recommended: Install to project (local)
mkdir -p .claude/skills
curl -o .claude/skills/depmap.md \
https://raw.githubusercontent.com/K-Dense-AI/claude-scientific-skills/main/scientific-skills/depmap/SKILL.mdSkill is scoped to this project only. Add .claude/skills/ to your .gitignoreif you don't want to commit it.
Alternative: Clone full repo
git clone https://github.com/K-Dense-AI/claude-scientific-skillsThen reference at scientific-skills/depmap/SKILL.md